catastrophic hazard

This term is defined in ECSS-E-ST-32-01C Rev. 1 as
“>NASA STS or ISS payloads< potential risk situation that can result in a disabling or fatal personnel injury, loss of the NASA orbiter, ISS, ground facilities, or STS/ISS equipment [NSTS 1700.7 incl. ISS Addendum, paragraph 302]"